March 28,2007: FDA Launches Web Page Warning Against Online Purchase of Accutane
The U.S. Food and Drug Administration (FDA) is launching a special Web page to warn consumers about the dangers of buying isotretinoin (Accutane) online. Improperly used, isotretinoin can cause severe side effects, including birth defects. Serious mental health problems have also been reported with isotretinoin use. This New FDA Web Page warns that the drug "should only be taken under the close supervision" of a physician or a pharmacist, and provides links to helpful information, including ways to check that drugs purchased online come from legitimate pharmacies.

December 30, 2005: National Accutane Registry Begins Taking Names
A national registry of Accutane users began accepting names on December 30, 2005. The "iPLEDGE" program, intended to keep track of persons currently using the anti-acne drug, requires health care providers and pharmacists to identify all patients who have been prescribed and/or sold Accutane, or any generic version of the drug (isotretinoin). The goal of the registry is to reduce the incidence of pregnancy-related harm caused by the drug, including birth defects and birth injuries. Go here for more information about the iPLEDGE program.

August 12, 2005: FDA Announces Accutane Registry Program
The U.S. Food and Drug Administration (FDA) approved a new distribution program for Accutane, meant to prevent use of the drug by pregnant women. Under the program (called iPLEDGE) doctors, pharmacists, and patients must enroll in a national registry and accept certain responsibilities before they may prescribe or use Accutane. Patients must also complete an "informed consent" form and agree to undergo counseling on safe use of Accutane, especially as to risks related to pregnancy. Go here